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Merck

LC/MS Analysis of CYP2D6 Inhibitors on Ascentis® Express HILIC

LC/MS Analysis of CYP2D6 Inhibitors on Ascentis® Express HILIC application for HPLC

Matériaux

Colonne analytique

Réf. du produit
Description
Tarif

53939-U

Ascentis® Express HILIC HPLC Column

2.7 μm particle size, L × I.D. 10 cm × 2.1 mm

Composant de phase mobile

Réf. du produit
Description
Tarif

70221

Formiate d′ammonium

eluent additive for LC-MS, LiChropur™, ≥99.0%

Étalon

Réf. du produit
Description
Tarif

I7379

Imipramine hydrochloride

≥99% (TLC)

1500218

Paroxetine hydrochloride

United States Pharmacopeia (USP) Reference Standard

PHR1384

Amitriptyline hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

PHR1394

Fluoxétine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

CONDITIONS

column

Ascentis Express HILlC, 10 cm x 2.1 mm I.D., 2.7 μm particles (53939-U)

mobile phase

5 mM ammonium formate in 2:98 (v/v) water:acetonitrile

flow rate

1.2 mL/min

column temp.

50 °C

detector

ESI(+), m/z 100-400

injection

0.5 μL

Description

Remarque sur l'analyse

This application demonstrates the suitability of the Ascentis Express HILIC for the analysis of CYP2D6 Inhibitors.

Informations légales

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Chromatogram Search

Related Product Categories

HPLC ColumnsGC Columns & AccessoriesTLC Plates & AdsorbentsSolid Phase Microextraction (SPME)Solid Phase Extraction & QuEChERS

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Small Molecule HPLCLarge Molecule HPLCGas Chromatography (GC)TLCSolid Phase Microextraction (SPME)Solid Phase Extraction (SPE)QuEChERS