Accéder au contenu
Merck

Teratology study in mice subjected to inhalation of diethylhydroxylamine, nitroethane, and diethylamine hydrogen sulfite.

Environmental research (1978-10-01)
R P Beliles, S L Makris, F Ferguson, C Putman, W Sapanski, N Kelly, K Partymiller, J Heicklen
PMID318511
RÉSUMÉ

Pregnant female mice were exposed from Days 6 to 17 of pregnancy to 8.9 +/- 2.0 ppm of diethylhydroxylamine and 14.3 +/- 2.0 ppm of nitroethane. Exposures were for 8.25 +/- 2.25 hours/day including weekends. The mice were also exposed continuously for 24 hours a day to the vapor of diethylamine hydrogen sulfite. The exposure produced no effect on the dams compared to the control group. There was no evidence of compound-induced terata, variation in sex ratio, embryotoxicity, or inhibition of fetal growth and development.

MATÉRIAUX
Référence du produit
Marque
Description du produit

Sigma-Aldrich
N,N-Diethylhydroxylamine, ≥98%