- Functionalizing bacterial cell surfaces with a phage protein.
Functionalizing bacterial cell surfaces with a phage protein.
Chemical communications (Cambridge, England) (2012-12-19)
Yi-Chun Yeh, Jana Müller, Changhao Bi, Nathan J Hillson, Harry R Beller, Swapnil R Chhabra, Steven W Singer
PMID23247551
RÉSUMÉ
Functionalization of bacterial cell surfaces has the potential to introduce new activities by chemical modification. Here we show that a bacteriophage-receptor complex can be used to functionalize the surface of two Gram-negative proteobacteria, Escherichia coli and Ralstonia eutropha with CdSe/ZnS nanoparticles. This work highlights the potential for using microbe-phage interactions to generate new functions on living cells.