- Highly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-beta-lactam core of chartellines.
Highly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-beta-lactam core of chartellines.
Chemical communications (Cambridge, England) (2009-10-15)
Shigeki Sato, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi
PMID19826689
RÉSUMÉ
A versatile, highly enantiocontrolled entry to the spiro-beta-lactam core of chartellines has been developed by expanding the scope of oxidative nitrogen atom transfer methodology based on chiral Rh-nitrenoid species.
MATÉRIAUX