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Key Documents

39294

Sigma-Aldrich

Fluo 3-AM solution

1 mM in DMSO, ≥99.0% (TLC)

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About This Item

Formule empirique (notation de Hill):
C51H50Cl2N2O23
Numéro CAS:
Poids moléculaire :
1129.85
Code UNSPSC :
12171500
Nomenclature NACRES :
NA.32

Niveau de qualité

Pureté

≥99.0% (TLC)

Forme

liquid

Concentration

1 mM in DMSO

Fluorescence

λex 506 nm; λem 525.0 nm±5.0 nm in 0.1 M Tris pH 8.0, esterase

Température de stockage

−20°C

Description générale

Cell permeable fluorescent indicator of intracellular Ca2+; non-fluorescent until it is hydrolyzed intracellularly and/or in the presence of Ca2+; lower binding affinity allows measurement of higher peaks of Ca2+ transients than with Fura 2.

Application

suitable as fluorescent Ca sensitive probe (after cleavage of the AM ester)

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

188.6 °F

Point d'éclair (°C)

87 °C


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Shiwen Han et al.
Scientific reports, 7(1), 7222-7222 (2017-08-05)
Glycyrrhizic acid (GA), the major bioactive triterpene glycoside of glycyrrhiza, has been shown to possess a wide range of pharmacological properties, including anti-inflammatory and anti-viral properties. However, few studies have examined the anti-allergic activity and exact mechanism of action of
Tamagno Pesqueira et al.
Scientific reports, 7(1), 10948-10948 (2017-09-10)
Magnetotherapy has been receiving increased attention as an attractive strategy for modulating cell physiology directly at the site of injury, thereby providing the medical community with a safe and non-invasive therapy. Yet, how magnetic field influences tendon cells both at
Yueliang Zhao et al.
Food & function, 10(5), 2729-2738 (2019-05-01)
Brosimone I is an isoprenoid-substituted flavonoid from Artocarpus heterophyllus. Here, we reported for the first time that brosimone I induced cell cycle G1 phase arrest and apoptosis in HCT116 human colon cancer cells. Brosimone I treatment increased the cytosolic Ca2+
Shrawan Kumar Mishra et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(2), 158-167 (2018-11-26)
Human GLTP on chromosome 12 (locus 12q24.11) encodes a 24 kD amphitropic lipid transfer protein (GLTP) that mediates glycosphingolipid (GSL) intermembrane trafficking and regulates GSL homeostatic levels within cells. Herein, we provide evidence that GLTP overexpression inhibits the growth of
Ruo-Xiao Cheng et al.
Theranostics, 9(15), 4287-4307 (2019-07-10)
Methylglyoxal (MGO), an endogenous reactive carbonyl compound, plays a key role in the pathogenesis of diabetic neuropathy. The aim of this study is to investigate the role of MGO in diabetic itch and hypoalgesia, two common symptoms associated with diabetic

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