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Key Documents

901798

Sigma-Aldrich

Fluorescent nanodiamond

Nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, biotin functionalized, PEG 3000 coated, 1 mg/mL in deionized water

Synonyme(s) :

Fluorescent nanoparticles, Nanodiamonds

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About This Item

Code UNSPSC :
12352100
Nomenclature NACRES :
NA.23

Forme

nanoparticles

Composition

Nitrogen vacancy, ~3 ppm NV centers

Concentration

1 mg/mL in deionized water

Taille moy. des particules

140 nm

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Description générale

Fluorescent nanodiamond (nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, biotin functionalized, PEG 3000 coated, 1 mg/mL in deionized water), a biocompatible carbon-based nanomaterial, has interesting properties like excellent photostability, low toxicity and facile surface functionalizability. It can be used for a variety of biological applications.

Application

Nanodiamonds (NDs) containing NV color centers exhibit fluorescence in red/near infra-red (NIR) region. The fluorescence in NDs originates from nitrogen vacancies and, unlike quantum dots and organic dyes, NDs do not photobleach. Fluorescent NDs find applications in background-free imaging, flow cytometry, super-resolution imaging etc. Our biotin functionalized NDs are ideal for attachment with streptavidin modified targets.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Functionality is Key: Recent Progress in the Surface Modification of Nanodiamond.
Krueger A, et al.
Advances in Functional Materials, 22, 890-890 (2012)
The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent
Vaijayanthimala V, et al.
Biomaterials, 33(31), 7794-7802 (2012)
Nanodiamond bioconjugate probes and their collection by electrophoresis.
Hens SC, et al.
Diamond and Related Materials, 17, 1858-1858 (2008)
Highly Fluorescent Nanodiamonds Protein-Functionalized for Cell Labeling and Targeting.
Chang B, et al.
Advances in Functional Materials, 23, 5737-5737 (2013)
Yuen Yung Hui et al.
Optics express, 18(6), 5896-5905 (2010-04-15)
Dynamics of fluorescent diamond nanoparticles in HeLa cells has been studied with two-photon fluorescence correlation spectroscopy (FCS). Fluorescent nanodiamond (FND) is an excellent fluorescent probe for bioimaging application, but they are often trapped in endosomes after cellular uptake. The entrapment
Afficher tous les articles scientifiques apparentés

Articles

Fluorescent Nanodiamond Particles: Properties and Applications

Fluorescent Nanodiamond Particles (FNDs)- Find properties and applications of nanodiamond particles.

Functionalization of Fluorescent Nanodiamonds for Bioimaging

Properties & characteristics of Fluorescent Nanodiamonds & biofunctionalization strategies explained. Conjugation protocols for streptavidin functionalization, biotinylation & coupling biotinylated/streptavidin provided. FNDs may be used for labeling of low-level expressed targets, Bioimaging & Bioconjugation.

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