XIAP
X-linked inhibitor of apoptosis
Synonymes:
API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3
Espèce(s):
Human XIAP (331), Mouse Xiap (11798), Rat Xiap (63879), Zebrafish xiap (373108), domestic cat XIAP (101090594), Horse XIAP (100060870), dog XIAP (442989), chicken XIAP (395280), domestic guinea pig Xiap (100715778), naked mole-rat Xiap (101715865) ...Plus
ID UniProtKB:
ID du gène:
- Human(331) Summary: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
- Mouse(11798) X-linked inhibitor of apoptosis
- Rat(63879) X-linked inhibitor of apoptosis
- Zebrafish(373108) X-linked inhibitor of apoptosis
- domestic cat(101090594) X-linked inhibitor of apoptosis
- Horse(100060870) X-linked inhibitor of apoptosis
- dog(442989) X-linked inhibitor of apoptosis
- chicken(395280) X-linked inhibitor of apoptosis
- domestic guinea pig(100715778) X-linked inhibitor of apoptosis
- naked mole-rat(101715865) X-linked inhibitor of apoptosis
- Domestic Rabbit(100328700) X-linked inhibitor of apoptosis
- cow(281647) X-linked inhibitor of apoptosis
- sheep(101116381) X-linked inhibitor of apoptosis
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ELISA
Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-XIAP antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-XIAP Antibody, clone 3H4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho-XIAP (pSer87) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
western blot
Anti-XIAP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
[KO Validated]Anti-XIAP Antibody, clone 5S5Q7, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
immunoprecipitation (IP)
western blot
western blot
Proteins
Référence du produit
Description
Espèce(s)
XIAP Active human, recombinant, expressed in baculovirus infected insect cells, ≥65% (SDS-PAGE),
Espèce(s)
human
XIAP, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human