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Merck

TTR

transthyretin

Synonymes:
CTS, CTS1, HsT2651, PALB, TBPA
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(7276) Summary: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]
  • Mouse(22139) transthyretin
  • Rat(24856) transthyretin
  • fruit fly(246932) tetrapter
  • domestic cat(101085927) transthyretin
  • dog(480167) transthyretin
  • chicken(396277) transthyretin
  • Zebrafish(449556) transthyretin (prealbumin, amyloidosis type I)
  • cow(280948) transthyretin
  • sheep(443389) transthyretin
  • domestic guinea pig(100735950) transthyretin
  • naked mole-rat(101726783) transthyretin

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Diphenyl ether, ReagentPlus®, ≥99%,
Espèce(s)
human
Diphenyl ether, ≥99%, FG,
Espèce(s)
human
N-Phenylanthranilic acid, 98%,
Espèce(s)
human
Diphenyl ether, ReagentPlus®, 99%,
Espèce(s)
human
L-Thyroxine, ≥98% (HPLC),
Espèce(s)
human, mouse, rat

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-TTR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-TTR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0290, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-TTR antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
canine, human, mouse, rat
Application
ELISA
immunohistochemistry
Anti-Transthyretin Antibody, clone 7G8-E11-E7, clone 7G8-E11-E7, from mouse,
Espèces réactives
human
Application
ELISA
western blot
Anti-Transthyretin antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Ligand

Référence du produit
Description
Espèce(s)
L-Thyroxine, ≥98% (HPLC),
Espèce(s)
human, mouse, rat
L-Thyroxine, powder, BioReagent, suitable for cell culture,
Espèce(s)
human, mouse, rat

Proteins

Référence du produit
Description
Espèce(s)
Prealbumin from human plasma, lyophilized powder,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human TTR,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ttr,
Espèce(s)
mouse