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Merck

THRA

thyroid hormone receptor, alpha

Synonymes:
AR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, c-ERBA-1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(7067) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(21833) thyroid hormone receptor alpha
  • Rat(81812) thyroid hormone receptor alpha
  • chicken(396251) thyroid hormone receptor, alpha
  • domestic cat(101095056) thyroid hormone receptor, alpha
  • dog(403601) thyroid hormone receptor, alpha
  • cow(532621) thyroid hormone receptor, alpha
  • sheep(443446) thyroid hormone receptor, alpha
  • naked mole-rat(101726699) thyroid hormone receptor, alpha
  • Domestic Rabbit(100303772) thyroid hormone receptor, alpha
  • domestic guinea pig(100726737) thyroid hormone receptor, alpha

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
3,3′,5-Triiodo-L-thyronine (T3) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
L-Thyroxine (T4) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Levothyroxine, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Levothyroxine sodium hydrate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Liothyronine, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Espèce(s)
rat, human
3,3′,5-Triiodo-L-thyronine, ≥95% (HPLC), powder,
Espèce(s)
rat, human
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Espèce(s)
rat, human
3,3′,5-Triiodothyroacetic acid, ≥90%,
Espèce(s)
rat, human
L-Thyroxine, ≥98% (HPLC),
Espèce(s)
human, mouse, rat

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Thyroid Hormone Receptor α, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-THRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-THRA antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
bovine, canine, human, mouse, pig, rat
Application
ELISA
western blot
Anti-THRA antibody produced in rabbit biotin conjugated, affinity isolated antibody,
Espèces réactives
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Application
Anti-THRA antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Espèces réactives
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Application

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
3,3′,5-Triiodo-L-thyronine sodium salt, powder, BioReagent, suitable for cell culture,
Espèce(s)
rat, human
3,3′,5-Triiodo-L-thyronine, ≥95% (HPLC), powder,
Espèce(s)
rat, human
3,3′,5-Triiodo-L-thyronine sodium salt, γ-irradiated, powder, suitable for, suitable for cell culture,
Espèce(s)
rat, human

Proteins

Référence du produit
Description
Espèce(s)
Thyroid Hormone receptor,α1 human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Espèce(s)
human
TR, α1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human THRA,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Thra,
Espèce(s)
mouse