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Merck

SCARB2

scavenger receptor class B, member 2

Synonymes:
AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(950) Summary: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(12492) scavenger receptor class B, member 2
  • Rat(117106) scavenger receptor class B, member 2
  • cow(533177) scavenger receptor class B, member 2
  • sheep(101105502) scavenger receptor class B, member 2
  • Domestic Rabbit(100352345) scavenger receptor class B, member 2
  • naked mole-rat(101715798) scavenger receptor class B, member 2
  • domestic guinea pig(100716020) scavenger receptor class B, member 2
  • Zebrafish(192340) scavenger receptor class B, member 2
  • domestic cat(101098789) scavenger receptor class B, member 2
  • dog(478435) scavenger receptor class B, member 2
  • chicken(422638) scavenger receptor class B, member 2

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ELISA

Référence du produit
Description
Espèce(s)
Human LIMP-II ELISA Kit, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-SCARB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-LIMP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-SCARB2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-SR-B2/LIMPII antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-LIMP II Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Scarb2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human SCARB2,
Espèce(s)
human