RFX5
regulatory factor X, 5 (influences HLA class II expression)
Synonymes:
Espèce(s):
Human RFX5 (5993), Mouse Rfx5 (53970), Rat Rfx5 (310659), cow RFX5 (539884), sheep RFX5 (101115494), Domestic Rabbit RFX5 (100328902), naked mole-rat Rfx5 (101698005), domestic guinea pig Rfx5 (100719654), Horse RFX5 (100055472), domestic cat RFX5 (101099317)
ID UniProtKB:
ID du gène:
- Human(5993) Summary: A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq, Jul 2008]
- Mouse(53970) regulatory factor X, 5 (influences HLA class II expression)
- Rat(310659) regulatory factor X, 5 (influences HLA class II expression)
- cow(539884) regulatory factor X, 5 (influences HLA class II expression)
- sheep(101115494) regulatory factor X, 5 (influences HLA class II expression)
- Domestic Rabbit(100328902) regulatory factor X, 5 (influences HLA class II expression)
- naked mole-rat(101698005) regulatory factor X, 5 (influences HLA class II expression)
- domestic guinea pig(100719654) regulatory factor X, 5 (influences HLA class II expression)
- Horse(100055472) regulatory factor X, 5 (influences HLA class II expression)
- domestic cat(101099317) regulatory factor X, 5 (influences HLA class II expression)
- dog(483197) regulatory factor X, 5 (influences HLA class II expression)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-Rfx5 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-RFX5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-RFX5 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
bovine, canine, human, mouse, pig, rat
Application
ELISA
western blot
western blot
Anti-RFX5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot
western blot
Anti-RFX5 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot