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Merck

PDK2

pyruvate dehydrogenase kinase, isozyme 2

Synonymes:
PDHK2, PDKII
Espèce(s):
Human PDK2 (5164), Mouse Pdk2 (18604), Rat Pdk2 (81530), domestic guinea pig Pdk2 (100734517), naked mole-rat Pdk2 (101699994), cow PDK2 (524075), sheep PDK2 (101108929), Zebrafish pdk2 (393971), dog PDK2 (491075), domestic cat PDK2 (101100013)
ID UniProtKB:
Q15119, A8K3A7, B3KNW0, Q6P515, Q9BS05
ID du gène:
  • Human(5164) Summary: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(18604) pyruvate dehydrogenase kinase, isoenzyme 2
  • Rat(81530) pyruvate dehydrogenase kinase, isozyme 2
  • domestic guinea pig(100734517) pyruvate dehydrogenase kinase, isozyme 2
  • naked mole-rat(101699994) pyruvate dehydrogenase kinase, isozyme 2
  • cow(524075) pyruvate dehydrogenase kinase, isozyme 2
  • sheep(101108929) pyruvate dehydrogenase kinase, isozyme 2
  • Zebrafish(393971) pyruvate dehydrogenase kinase, isoenzyme 2
  • dog(491075) pyruvate dehydrogenase kinase, isozyme 2
  • domestic cat(101100013) pyruvate dehydrogenase kinase, isozyme 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA008287
Anti-PDK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
SAB4502155
Anti-PDK2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
WH0005164M2
Monoclonal Anti-PDK2 antibody produced in mouse, clone 5F8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
ST1643
Anti-PDK2 Mouse mAb (2G1), liquid, clone 2G1, Calbiochem®,
Espèces réactives
human
Application
SAB1406241
Anti-PDK2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
347795
Sodium dichloroacetate, 98%,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
SRP5248
PDHK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU028791
MISSION® esiRNA, targeting human PDK2,
Espèce(s)
human
EMU052061
MISSION® esiRNA, targeting mouse Pdk2,
Espèce(s)
mouse