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Merck

NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Synonymes:
NFAT1, NFATP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4773) Summary: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
  • Mouse(18019) nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
  • Rat(311658) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • chicken(419346) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • domestic cat(101080520) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • cow(530401) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • Horse(100052657) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • dog(485930) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • sheep(101119239) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • domestic guinea pig(100722868) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • naked mole-rat(101722005) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-NFATC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-NFAT1 Antibody, clone 8G4.2, clone 8G4.2, Upstate®, from mouse,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
western blot
Anti-NFATC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-phospho-NFAT1 (pSer54) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
mouse
Application
western blot
Anti-NFATC2 antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
human, mouse
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
NFAT Inhibitor, >96% (HPLC), solid,
Espèce(s)
mouse, human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human NFATC2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Nfatc2,
Espèce(s)
mouse