Accéder au contenu
Merck

NEFL

neurofilament, light polypeptide

Synonymes:
CMT1F, CMT2E, NF-L, NF68, NFL
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
  • Mouse(18039) neurofilament, light polypeptide
  • Rat(83613) neurofilament, light polypeptide
  • chicken(419528) neurofilament, light polypeptide
  • cow(281348) neurofilament, light polypeptide
  • domestic cat(101081039) neurofilament, light polypeptide
  • dog(477378) neurofilament, light polypeptide
  • naked mole-rat(101704332) neurofilament, light polypeptide
  • domestic guinea pig(100731797) neurofilament, light polypeptide
  • sheep(101119539) neurofilament, light polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
Neurofilament (2F11) Mouse Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Anticorps anti-chaîne légère du neurofilament, serum, Chemicon®,
Espèces réactives
bovine, canine, feline, human, mouse, pig, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Neurofilament 68 antibody produced in mouse, clone NR4, ascites fluid,
Espèces réactives
chicken, human, pig, rat
Application
immunohistochemistry
microarray

western blot
Anti-Neurofilament L Antibody, clone 1E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anticorps anti-neurofilament 70 kDa, clone DA2, culture supernatant, clone DA2, Chemicon®,
Espèces réactives
bovine, human, mouse, pig, rat
Application
immunocytochemistry
immunohistochemistry

western blot

Proteins

Référence du produit
Description
Espèce(s)
Neurofilament 70 kDa, porcine, ,
Espèce(s)

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human NEFL,
Espèce(s)
human