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Merck

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Synonymes:
C-Kit, CD117, PBT, SCFR
Espèce(s):
Human KIT (3815), Mouse Kit (16590), Rat Kit (64030), chicken KIT (378783), domestic cat KIT (493766), cow KIT (280832), Horse KIT (100009704), dog KIT (403811), Goat KIT (100861386), sheep KIT (780504) ...Plus
ID UniProtKB:
P10721, B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99
ID du gène:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

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ELISA

Référence du produit
Description
Espèce(s)
RAB0731
Human KIT / Mast/Stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Espèce(s)
human
RAB0992
Phosphotyrosine KIT / Mast/stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
07-806
Anti-phospho-c-Kit (Tyr568/Tyr570) Antibody, Upstate®, from rabbit,
Espèces réactives
human
Application
western blot
SAB4501648
Anti-C-KIT antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
CBL1360
Anti-CD117 Antibody, clone ACK2, clone ACK2, Chemicon®, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA004471
Anti-KIT antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
SAB4700750
Monoclonal Anti-CD117 antibody produced in mouse, clone 104D2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
bovine, human, nonhuman primates
Application
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
CDS022173
Imatinib, ,
Espèce(s)
human
PZ0012
Sunitinib malate, ≥98% (HPLC),
Espèce(s)
human
CDS023580
Pazopanib, ,
Espèce(s)
human
SML2589
Dasatinib, ≥98% (HPLC),
Espèce(s)
human
CDS023389
Dasatinib, ,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
14-559-M
c-Kit Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human Kit, amino acids 544-end, for use in Kinase Assays.,
Espèce(s)
human
14-611-M
c-Kit (D816V) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant human c-Kit, amino acids 544-end containing the D816V mutation, for use in Kinase Assays.,
Espèce(s)
human
SRP0342
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE),
Espèce(s)
human
SRP5299
c-KIT (D820E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
SRP5308
c-KIT (T670E), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EMU049661
MISSION® esiRNA, targeting mouse Kit,
Espèce(s)
mouse
EHU000841
MISSION® esiRNA, targeting human KIT,
Espèce(s)
human