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Merck

KCNA4

potassium voltage-gated channel, shaker-related subfamily, member 4

Synonymes:
HBK4, HK1, HPCN2, HUKII, KCNA4L, KCNA8, KV1.4, PCN2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3739) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.[provided by RefSeq, Mar 2011]
  • Mouse(16492) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Rat(25469) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Zebrafish(559036) potassium voltage-gated channel, shaker-related subfamily, member 4
  • chicken(395721) potassium voltage-gated channel, shaker-related subfamily, member 4
  • cow(281880) potassium voltage-gated channel, shaker-related subfamily, member 4
  • domestic cat(101084479) potassium voltage-gated channel, shaker-related subfamily, member 4
  • dog(485427) potassium voltage-gated channel, shaker-related subfamily, member 4
  • domestic guinea pig(100725985) potassium voltage-gated channel, shaker-related subfamily, member 4
  • naked mole-rat(101706863) potassium voltage-gated channel, shaker-related subfamily, member 4
  • sheep(101118217) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Domestic Rabbit(100328568) potassium voltage-gated channel, shaker-related subfamily, member 4

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-KCNA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-KCNA4 antibody produced in mouse, clone S13-31, 1 mg/mL, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Potassium Channel Kv1.4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Espèces réactives
mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Guanidine hydrochloride, for molecular biology, ≥99%,
Espèce(s)
human
Guanidine hydrochloride, ≥98%,
Espèce(s)
human
Guanidine hydrochloride, organic base and chaeotropic agent, ≥99% (titration),
Espèce(s)
human
Guanidine hydrochloride, ,
Espèce(s)
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human KCNA4,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Kcna4,
Espèce(s)
mouse