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Merck

CASP6

caspase 6, apoptosis-related cysteine peptidase

Synonymes:
MCH2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(839) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12368) caspase 6
  • Rat(83584) caspase 6
  • Zebrafish(552927) caspase 6, apoptosis-related cysteine peptidase
  • dog(487899) caspase 6, apoptosis-related cysteine peptidase
  • cow(538409) caspase 6, apoptosis-related cysteine peptidase
  • domestic cat(768261) caspase 6, apoptosis-related cysteine peptidase
  • chicken(395477) caspase 6, apoptosis-related cysteine peptidase
  • domestic guinea pig(100713360) caspase 6, apoptosis-related cysteine peptidase
  • naked mole-rat(101707090) caspase 6, apoptosis-related cysteine peptidase
  • sheep(101119820) caspase 6, apoptosis-related cysteine peptidase

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Antibodies

Référence du produit
Description
Espèces réactives
Application
ANTI-PHOSPHO-CASPASE 6(S257) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CASP6 (Cleaved-Asp162) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-Caspase 6 (pSer257) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
N-Acetyl-Val-Glu-Ile-Asp-al, ~99% (HPLC), powder,
Espèce(s)
human
Caspase Inhibitor, ,
Espèce(s)
human
NSCI, ≥97% (HPLC), solid,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CASP6,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Casp6,
Espèce(s)
mouse