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Merck

CACNA1E

calcium channel, voltage-dependent, R type, alpha 1E subunit

Synonymes:
BII, CACH6, CACNL1A6, Cav2.3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(777) Summary: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • Mouse(12290) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Rat(54234) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Zebrafish(567702) voltage-dependent R-type calcium channel subunit alpha-1E
  • cow(353113) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic cat(101093985) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • dog(490305) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • chicken(424412) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • naked mole-rat(101701145) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic guinea pig(100716749) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • sheep(101102503) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Domestic Rabbit(100009403) calcium channel, voltage-dependent, R type, alpha 1E subunit

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Small Molecule - Allosteric Modulator

Référence du produit
Description
Espèce(s)
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-Dihydropyridine Receptor (α1 Subunit) antibody produced in mouse, clone 1A, buffered aqueous solution,
Espèces réactives
guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Verapamil hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Amlodipine besylate, ≥98% (HPLC),
Espèce(s)
human
Amlodipine besylate, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Amlodipine besylate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Nicardipine hydrochloride, powder, ≥98%,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Cacna1e,
Espèce(s)
mouse
MISSION® esiRNA, targeting human CACNA1E,
Espèce(s)
human
MISSION® esiRNA, targeting human CACNA1S,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cacna1s,
Espèce(s)
mouse