BIRC3
baculoviral IAP repeat containing 3
- Human(330) Summary: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
- Mouse(11796) baculoviral IAP repeat-containing 3
- Rat(78971) baculoviral IAP repeat-containing 3
- domestic guinea pig(100713574) baculoviral IAP repeat containing 3
- naked mole-rat(101719143) baculoviral IAP repeat containing 3
- sheep(101120189) baculoviral IAP repeat containing 3
- dog(489433) baculoviral IAP repeat containing 3
- domestic cat(101083444) baculoviral IAP repeat containing 3
- Horse(100068894) baculoviral IAP repeat containing 3
- cow(514386) baculoviral IAP repeat containing 3
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