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Merck

ARHGAP35

Rho GTPase activating protein 35

Synonymes:
GRF-1, GRLF1, P190-A, P190A, p190ARhoGAP, p190RhoGAP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2909) Summary: The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008]
  • Rat(306400) Rho GTPase activating protein 35
  • Zebrafish(564565) Rho GTPase activating protein 35b
  • cow(540310) Rho GTPase activating protein 35
  • chicken(425730) Rho GTPase activating protein 35
  • dog(403543) Rho GTPase activating protein 35
  • domestic cat(101089912) Rho GTPase activating protein 35
  • sheep(101117354) Rho GTPase activating protein 35
  • domestic guinea pig(100718086) Rho GTPase activating protein 35
  • naked mole-rat(101719355) Rho GTPase activating protein 35

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ARHGAP35 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-phospho-GRF-1 (pTyr1105) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-ARHGAP35 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ARHGAP35,
Espèce(s)
human