AGTR1
angiotensin II receptor, type 1
Synonymes:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Espèce(s):
Human AGTR1 (185), naked mole-rat Agtr1 (101714068), domestic guinea pig Agtr1 (100192325), sheep AGTR1 (443107), Domestic Rabbit AGTR1 (100009164), chicken AGTR1 (396065), domestic cat AGTR1 (101082936), dog AGTR1 (403836), cow AGTR1 (281607)
ID UniProtKB:
ID du gène:
- Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
- naked mole-rat(101714068) angiotensin II receptor, type 1
- domestic guinea pig(100192325) angiotensin II receptor, type 1
- sheep(443107) angiotensin II receptor, type 1
- Domestic Rabbit(100009164) angiotensin II receptor, type 1
- chicken(396065) angiotensin II receptor, type 1
- domestic cat(101082936) angiotensin II receptor, type 1
- dog(403836) angiotensin II receptor, type 1
- cow(281607) angiotensin II receptor, type 1
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Small Molecule - Agonist
Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Olmesartan Medoxomil, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Losartan Potassium, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
Espèces réactives
human, mouse, rat
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, canine, human, mouse, rat
Application
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
Application
western blot
Anti-AT1R/AGTR1 Antibody, clone 8W6G0, Rabbit Monoclonal, ,
Espèces réactives
human
Application
western blot
Small Molecule - Inhibitor
Proteins
Référence du produit
Description
Espèce(s)
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Espèce(s)
human
esiRNA
Référence du produit
Description
Espèce(s)