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  • Gamma butyrolactone poisoning and its similarities to gamma hydroxybutyric acid: two case reports.

Gamma butyrolactone poisoning and its similarities to gamma hydroxybutyric acid: two case reports.

Veterinary and human toxicology (1997-08-01)
M O Rambourg-Schepens, M Buffet, C Durak, M Mathieu-Nolf
ABSTRACT

Clinical experience with toxicity induced by products containing gamma butyrolactone is limited. We report here 2 cases of gamma butyrolactone poisoning with a nail polish remover labelled "acetone-free". Rapid onset of coma, respiratory depression and bradycardia occurred in both patients. After supportive care, they fully recovered within a few hours.

MATERIALS
Product Number
Brand
Product Description

Supelco
γ-Butyrolactone, analytical standard
Sigma-Aldrich
γ-Butyrolactone, ReagentPlus®, ≥99%
Sigma-Aldrich
4-Hydroxybutanoic acid lactone, ≥98%, FCC, FG