SML3553
STF-1084
≥98% (HPLC)
Synonym(s):
ENPP1 inhibitor Compound 15, P-[2-[1-(6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl]ethyl]-phosphonic acid
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C17H24N3O5P
CAS Number:
Molecular Weight:
381.36
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=P(O)(O)CCC(CC1)CCN1C2=NC=NC3=C2C=C(OC)C(OC)=C3
Biochem/physiol Actions
STF-1084 (ENPP1 inhibitor Compound 15) Is a cell-impermeable, potent, selective, stable and nontoxic competitive inhibitor of ENPP1 (ectonucleotide pyrophosphatase phosphodiesterase 1) that inhibit degradation of extracellular cGAMP under physiological conditions. STF-1084 had no effect on intracellular cGAMP. STF-1084 synergized with IR to significantly delay tumor progression in three triple-negative breast cancer cell lines 4T1-luc mice model.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service