RAB0412

PTH / Parathyroid Hormone EIA Kit

for serum, plasma, culture supernatant and cell lysates

• Synonym(s): PTH, Parathyroid hormone, PTH1, Parathormone, Parathyrin
• UNSPSC Code: 41116158
• NACRES: NA.32

Properties

• species reactivity: rat, human, mouse
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable; enzyme immunoassay: suitable
• input: sample type plasma; sample type cell lysate; sample type serum; sample type culture supernatant(s)
• assay range: inter-assay cv: <15%; intra-assay cv: <10%; sensitivity: 1.27 pg/mL; standard curve range: 1-1000 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... PTH(5741)

Description

General description

The PTH Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting PTH peptide based on the principle of Competitive Enzyme Immunoassay.

Immunogen

Parathyroid Hormone (PTH), synthetic peptide

Application

PTH / arathyroid hormone EIA kit has been used to determine parathyroid hormone (PTH) levels in human embryonic kidney (HEK293) cells.

Biochem/physiol Actions

Parathyroid hormone (PTH) plays a vital role in regulation calcium homeostasis. It increases bone mass in animals and humans by inhibiting osteoblast apoptosis. PTH has potential applications in preventing fractures in postmenopausal women with osteoporosis. Irregular diurnal patterns of PTH leads to sustained mild hypercalcemia in non dialyzed chronic kidney disease (CKD) patients. PTH, along with other heart failure biomarkers play a vital role in measuring disease severity and prognosis of heart failure with preserved ejection fraction (HFpEF). Variation in PTH leads to osteoporosis in asymptomatic hyperparathyroidism (HPT).

Kit Components Also Available Separately

• RABHRP3 HRP-Streptavidin

Safety Information

• Pictograms: GHS05
• Signal Word: Warning
• Hazard Statements: H290
• Precautionary Statements: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials