C0250

Sodium cacodylate trihydrate

≥98%

• Synonym(s): Cacodylic acid sodium salt trihydrate, Dimethylarsinic acid sodium salt, Dimethylarsonic acid sodium salt
• Linear Formula: (CH₃)₂AsO₂Na · 3H₂O
• CAS Number: 6131-99-3
• Molecular Weight: 214.03
• Beilstein: 3702348
• EC Number: 204-708-2
• MDL number: MFCD00149079
• UNSPSC Code: 12161700
• PubChem Substance ID: 24892242
• NACRES: NA.21

Properties

• Assay: ≥98%
• form: powder
• pH: 5.1-7.4
• pKa (25 °C): 6.27
• solubility: water: 100 mg/mL, clear, colorless
• application(s): ADME/TOX
• storage temp.: room temp
• SMILES string: [Na+].[H]O[H].[H]O[H].[H]O[H].C[As](C)([O-])=O
• InChI: 1S/C2H7AsO2.Na.3H2O/c1-3(2,4)5;;;;/h1-2H3,(H,4,5);;3*1H2/q;+1;;;/p-1
• InChI key: RLGWPHBPRCROJO-UHFFFAOYSA-M

Description

General description

Sodium cacodylate is an organic arsenic compound that is metabolized to produce inorganic, trivalent arsenic in vivo. Sodium cacodylate has been used as a source of arsenic in toxicological research. It is used as a buffer with an effective pH buffering range of 5.1-7.4. In microscopy studies, the buffering capacity of cacodylate prevents excess acidity that may result from tissue fixation.

Application

Sodium cacodylate trihydrate has been used in the stabilization of the fixatives for electron microscopy. It has also been used to collect vibratome sections to perform nucleoside-diphosphatase technique.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H301 + H331,H350,H410
• Precautionary Statements: P202 - P261 - P264 - P273 - P301 + P310 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B
• Storage Class Code: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves