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33699

Supelco

Enrofloxacin

VETRANAL®, analytical standard

Synonym(s):

Baytril

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About This Item

Empirical Formula (Hill Notation):
C19H22FN3O3
CAS Number:
93106-60-6
Molecular Weight:
359.39
Beilstein:
5307824
MDL number:
MFCD00792463
UNSPSC Code:
41116107
PubChem Substance ID:
329754634
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

clinical testing

format

neat

Mode of action

DNA synthesis | interferes
enzyme | inhibits

SMILES string

CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4

InChI

1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)

InChI key

SPFYMRJSYKOXGV-UHFFFAOYSA-N

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General description

Chemical structure: fluoroquinolone
Enrofloxacin is a broad-spectrum fluoroquinolone antibiotic extensively used in human and veterinary medicines. The drug acts by inhibiting bacterial DNA gyrase and DNA Topoisomerase IV (Topo IV), which are the vital enzymes responsible for DNA replication.

Application

Enrofloxacin may be used as an analytical reference standard for the determination of the analyte in bovine milk, pig plasma, goat milk, and food samples by various analytical techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H317,H334

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK2874
BCBZ6597
SZBE199XV
SZBD053XV
SZBA336XV

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Determination of enrofloxacin and its metabolite ciprofloxacin in goat milk by high-performance liquid chromatography with diode-array detection: Optimization and validation
Cinquina AL, et al.
Journal of Chromatography A, 987(1-2), 221-226 (2003)
Determination of residual enrofloxacin in food samples by a sensitive method of chemiluminescence enzyme immunoassay
Yu F, et al.
Food Chemistry, 149, 71-75 (2014)
Sook Mei Khor et al.
Analytical and bioanalytical chemistry, 405(11), 3889-3898 (2013-02-27)
A displacement immunoassay involves having a labelled analogue of the analyte (the epitope) already bound to the antibody. The presence of the analyte causes a competition for antibodies, and some of the antibodies dissociates from the epitope so that it
Kristine H Wammer et al.
Water research, 47(1), 439-448 (2012-11-13)
Fluoroquinolone (FQ) antibacterial compounds are frequently detected in the aquatic environment, and photodegradation is expected to play an important role in FQ fate in some sunlit surface waters. This study investigated the direct aquatic photochemistry of three FQs: norfloxacin, ofloxacin
Jochen Springer et al.
Stroke, 45(12), 3675-3683 (2014-10-30)
Muscle wasting is a common complication accompanying stroke. Although it is known to impair poststroke recovery, the mechanisms of subacute catabolism after stroke have not been investigated in detail. The aim of this study is to investigate mechanisms of local
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