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MAB5740

Sigma-Aldrich

Anti-Radial Glial Cell Marker-2 Antibody, clone RC2

clone RC2, from mouse

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1 G
SGD 1,620.00

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

SGD 1,620.00

Please contact Customer Service for Availability

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

RC2, monoclonal

species reactivity

mouse

technique(s)

immunohistochemistry: suitable

isotype

IgMλ

shipped in

wet ice

target post-translational modification

unmodified

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Gene Information

human ... C9ORF72(203228)

Gene Information

human ... C9orf72(203228)

Gene Information

human ... C9orf72(203228)

Gene Information

human ... C9orf72(203228)

biological source

rat

biological source

rat

biological source

rabbit

biological source

rabbit

clone

5A2, monoclonal

clone

14E2, monoclonal

clone

polyclonal

clone

polyclonal

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

serum

antibody form

affinity isolated antibody

technique(s)

immunohistochemistry: suitable, western blot: suitable

technique(s)

immunocytochemistry: suitable, western blot: suitable

technique(s)

dot blot: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

General description

The monoclonal antibody Radial Glial Cell Marker-2, clone RC2 (RC2) was generated in mouse by conventional hybridoma methodology. The antigen recognized by RC2 is robust, allowing aldehyde fixation appropriate to high resolution light and electron microscopic analyses. From the neural tube stage of fetal development the antibody delineates throughout the central nervous system a subpopulation of neuroepithelial cells which have a radial bipolar morphology. RC2 also recognizes monopolar cell forms in the spinal cord and the cerebellum as early as E15, and in the dentate gyrus of the hippocampal formation from the day of birth. Monopolar forms in the cerebellum are inferred to be progenitors of Bergmann glia. The robustness of the antigen recognized by RC2 makes this probe a valuable tool to study the morphological transformations of the bipolar radial glia during their mitotic turnover. It also provides a sensitive stain for the study of the organization and the histogenetic role of the overall radial fiber system (3).

Specificity

Detects radial glial cell marker-2
Other species have not been tested.

Immunogen

Embryonic rat brain

Application

Anti-Radial Glial Cell Marker-2 Antibody, clone RC2 detects level of Radial Glial Cell Marker-2 & has been published & validated for use in IH.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Physical form

Ammonium sulfate purified mouse monoclonal in PBS with 0.05% NaN3.
Format: Purified

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

    • Certificates of Analysis (COA)

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