1.09162

Tetra-n-butylammonium hydroxide solution

c[(C₄H₉)₄NOH] = 0.1 mol/l (0.1 N) in 2-propanol/methanol, reag. USP, ready-to-use volumetric solution for titration in non-aqueous media, Titriplex^®

• Synonym(s): Quaternary Ammonium Hydroxide Solution
• UNSPSC Code: 12352107
• NACRES: NA.21

Properties

• product name: Tetra-n-butylammonium hydroxide solution, in 2-propanol/methanol for titrations in nonaqueous media c[(C₄H₉)₄NOH] = 0.1 mol/l (0.1 N), Titripur^®, reag. USP
• Agency: reag. USP
• Quality Level: 200
• product line: Titripur^®
• form: liquid
• quality: Analyzed in our ISO 17025 accredited QC lab
• reaction suitability: reaction type: Acid-base reactions
• concentration: 0.1 M
• technique(s): titration: suitable
• pH: 14 (20 °C in H₂O)
• transition temp: flash point 12 °C
• density: 0.792 g/cm³ at 20 °C
• storage temp.: 15-25°C

Description

Application

• Simultaneous analysis of dehydroacetic acid, benzoic acid, sorbic acid and salicylic acid in cosmetic products by solid-phase extraction and high-performance liquid chromatography: This research highlights the application of Tetra-n-butylammonium hydroxide as as an ion-pair reagent in the chromatographic analysis of various acids in cosmetic products. The study showcases its effectiveness in enhancing the extraction and solubility of analytes, making it a valuable tool for chemists and researchers in pharmaceuticals and environmental testing (Mikami et al., 2002).

Features and Benefits

Accreditation:
This volumetric solution is analyzed by our calibration laboratory D-K-15185-01-00 which is accredited according to DIN EN ISO/IEC 17025 for analysis of amount-of-substance concentrations in volumetric solutions by DAkkS (Deutsche Akkreditierungsstelle - German National Accreditation Body). The accreditation certificate can be found at www.sigmaaldrich.com/ISO17025.

Packaging

SKU-pack size numbers ending with a "3" are SmartChemicals with an RFID tag on the label for seamless data transfer to the instrument, e.g. xxxxxx1003 or xxxxxxx 4003. More information on www.sigmaaldrich.com/SmartChemicals

Analysis Note

Form liquid
Amount-of-substance concentration 0.0994 - 1.006 mol/L
Measurement uncertainty ± 0.0004 mol/L
Traceability NIST SRM

The concentration is determined by volumetric titration and refers to 20°C.
The amount-of-substance concentration of this volumetric solution is traceable to a primary standard reference material (SRM) from the National Institute of Standards and Technology, Gaithersburg, USA (NIST SRM 350 benzoic acid) by means of volumetric standard benzoic acid (article number 1.02401), certified reference material according to ISO 17034, analyzed by our accredited calibration laboratory of Merck KGaA, Darmstadt, Germany according to DIN EN ISO/IEC 17025. The uncertainty is expressed as expanded measurement uncertainty with a coverage factor k=2 covering a confidence level of 95%.

Note: The titer is a correction factor to correct for variations of the volumetric solution, the titration equipment, the temperature and other laboratory conditions. For correct titration results it is recommended to determine a titer with the laboratory specific equipment and under laboratory specific conditions directly after opening a new bottle and at regular time intervals.

Legal Information

Titripur is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H302 + H312 + H332 - H314 - H317 - H336 - H370
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 1 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 53.6 °F
• Flash Point(C): 12 °C