A-046
Atropine solution
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
Synonym(s):
Atropine solution
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About This Item
Empirical Formula (Hill Notation):
C17H23NO3
CAS Number:
Molecular Weight:
289.37
UNSPSC Code:
41116107
NACRES:
NA.24
grade
certified reference material
form
liquid
feature
SNAP-N-SPIKE®. SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
InChI
1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3
InChI key
RKUNBYITZUJHSG-UHFFFAOYSA-N
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General description
A Certified Spiking Solution® suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from clinical toxicology to forensic analysis and pharmaceutical research. Atropine is a pharmaceutical drug used for treatment of cardiac conditions.
For the analysis of the phytotoxins. Tropane alkaloid.
For the analysis of the phytotoxins. Tropane alkaloid.
Application
- Atropine sulfate solution: Study conducted a systematic review and meta-analysis on the effectiveness of atropine in managing sialorrhea, highlighting its use as a muscarinic antagonist reagent in clinical settings, providing critical insights for pharmacological research atropine applications (Yellepeddi et al., 2024).
- Pharmacological research atropine: The clinical pharmacokinetics of an atropine oral gel formulation were studied in healthy volunteers, underscoring its importance in acetylcholine receptor studies and its application in developing pharmacokinetic profiles for pharmaceutical research (Parrot et al., 2024).
- Atropine as a muscarinic antagonist in pharmacological research: The study discussed the utility of plant alkaloids, including atropine, in treating eye diseases, illustrating atropine′s role as a vital ophthalmic research chemical and its broader implications in medical research (Lorrai et al., 2024).
- High purity atropine solution for biochemical studies: The study developed a new method for solvent suppression in pure shift NMR, enhancing the understanding of atropine′s interactions at the molecular level, which is crucial for advancing analytical standards for delta8-THC and related compounds in scientific research (Gates et al., 2024).
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
35.6 °F - closed cup
Flash Point(C)
2 °C - closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Marija Lukac et al.
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 23(1), 80-84 (2013-02-05)
Evaluation of the effectiveness of oral atropine versus surgical therapy for hypertrophic pyloric stenosis (HPS). A total of 66 consecutive patients with HPS were treated at the University Children's Hospital between January 2006 and December 2011. The diagnosis was initially
Max J Hilz et al.
Stroke, 44(4), 1062-1069 (2013-02-21)
Pharmacological blockade showed sympathetic origin of 0.03 to 0.15 Hz blood pressure (BP) oscillations and parasympathetic origin of 0.15 to 0.5 Hz RR-interval (RRI) oscillations, but has not been used to determine origin of cerebral blood flow velocity (CBFV) oscillations
Yasmin S Bradfield
American family physician, 87(5), 348-352 (2013-04-04)
Amblyopia is the leading cause of vision loss in children. It is treatable if diagnosed early, making identification of affected children critical. The American Association for Pediatric Ophthalmology and Strabismus and the American Academy of Pediatrics recommend that clinicians routinely
Feng Luo et al.
The European journal of neuroscience, 37(3), 393-399 (2013-02-05)
Brain cholinergic modulation is essential for learning-induced plasticity of the auditory cortex. The pedunculopontine tegmental nucleus (PPTg) is an important cholinergic nucleus in the brainstem, and appears to be involved in learning and subcortical plasticity. This study confirms the involvement
A I Strelnikova et al.
Bulletin of experimental biology and medicine, 154(2), 180-183 (2013-01-19)
Acetylcholine (5.5×10(-10)-5.5×10(-6)M) accelerated erythrocyte agglutination in men, non-pregnant women in follicular phase of the menstrual cycle, and pregnant women in the first trimester. The effect was blocked with atropine (5.5×10(-6)M). Acetylcholine had no effect on the rate of erythrocyte agglutination
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