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Merck

PYCR1

pyrroline-5-carboxylate reductase 1

Synonyms:
ARCL2B, ARCL3B, P5C, P5CR, PIG45, PP222, PRO3, PYCR
Species:
UniProtKB ID:
Gene ID:
  • Human(5831) Summary: This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(209027) pyrroline-5-carboxylate reductase 1
  • Rat(287877) pyrroline-5-carboxylate reductase 1
  • domestic guinea pig(100735068) pyrroline-5-carboxylate reductase 1
  • naked mole-rat(101719799) pyrroline-5-carboxylate reductase 1
  • cow(539606) pyrroline-5-carboxylate reductase 1
  • sheep(101113161) pyrroline-5-carboxylate reductase 1
  • Zebrafish(393799) pyrroline-5-carboxylate reductase 1
  • dog(483372) pyrroline-5-carboxylate reductase 1
  • domestic cat(101090664) pyrroline-5-carboxylate reductase 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PYCR1 Antibody, clone 2D9.1, clone 2D9.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PYCR1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-PYCR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PYCR1,
Species
human
MISSION® esiRNA, targeting mouse Pycr1,
Species
mouse