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Merck

PPAT

phosphoribosyl pyrophosphate amidotransferase

Synonyms:
ATASE, GPAT, PRAT
Species:
UniProtKB ID:
Gene ID:
  • Human(5471) Summary: The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]
  • Mouse(231327) phosphoribosyl pyrophosphate amidotransferase
  • Rat(117544) phosphoribosyl pyrophosphate amidotransferase
  • cow(509652) phosphoribosyl pyrophosphate amidotransferase
  • sheep(101109095) phosphoribosyl pyrophosphate amidotransferase
  • domestic guinea pig(100730194) phosphoribosyl pyrophosphate amidotransferase
  • naked mole-rat(101720775) phosphoribosyl pyrophosphate amidotransferase
  • Domestic Rabbit(100348590) phosphoribosyl pyrophosphate amidotransferase
  • Zebrafish(572027) phosphoribosyl pyrophosphate amidotransferase
  • chicken(422743) phosphoribosyl pyrophosphate amidotransferase
  • domestic cat(101084957) phosphoribosyl pyrophosphate amidotransferase
  • Horse(100053805) phosphoribosyl pyrophosphate amidotransferase
  • dog(611407) phosphoribosyl pyrophosphate amidotransferase

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PPAT antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PPAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PPAT antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-PPAT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PPAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
Azathioprine, ≥98%,
Species
human
6-Mercaptopurine monohydrate, 98%,
Species
human
Azathioprine, European Pharmacopoeia (EP) Reference Standard,
Species
human
Mercaptopurine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Azathioprine, United States Pharmacopeia (USP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PPAT,
Species
human
MISSION® esiRNA, targeting mouse Ppat,
Species
mouse