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Merck

P2RY1

purinergic receptor P2Y, G-protein coupled, 1

Synonyms:
P2Y1
Species:
UniProtKB ID:
Gene ID:
  • Human(5028) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
  • Mouse(18441) purinergic receptor P2Y, G-protein coupled 1
  • Rat(25265) purinergic receptor P2Y, G-protein coupled, 1
  • chicken(396275) purinergic receptor P2Y, G-protein coupled, 1
  • dog(449621) purinergic receptor P2Y, G-protein coupled, 1
  • domestic cat(101090795) purinergic receptor P2Y, G-protein coupled, 1
  • cow(281963) purinergic receptor P2Y, G-protein coupled, 1
  • sheep(101114407) purinergic receptor P2Y, G-protein coupled, 1
  • Domestic Rabbit(100353792) purinergic receptor P2Y, G-protein coupled, 1
  • domestic guinea pig(100135592) purinergic receptor P2Y, G-protein coupled 1

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Small Molecule - Agonist

Product Number
Description
Species
Adenosine 5′-diphosphate, ≥95% (HPLC),
Species
human
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
MRS 2179 ammonium salt hydrate, ≥98% (HPLC),
Species
human
Adenosine 5′-diphosphate monopotassium salt dihydrate, bacterial, ≥95%, powder,
Species
human
Adenosine 5′-diphosphate sodium salt, bacterial, ≥95% (HPLC),
Species
human
Adenosine 5′-diphosphate, ≥95% (HPLC),
Species
human
NF 023 hydrate, ≥98% (HPLC), solid,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-P2Y1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunohistochemistry
Anti-P2RY1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-P2RY1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-P2RY1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-P2RY1, (N-terminal) antibody produced in mouse, clone 4C2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Suramin sodium salt, ≥98% (TLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human P2RY1,
Species
human
MISSION® esiRNA, targeting mouse P2ry1,
Species
mouse