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Merck

MSH2

mutS homolog 2

Synonyms:
COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Species:
UniProtKB ID:
Gene ID:
  • Human(4436) Summary: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(17685) mutS homolog 2 (E. coli)
  • Rat(81709) mutS homolog 2 (E. coli)
  • Zebrafish(406845) mutS homolog 2 (E. coli)
  • chicken(378799) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • dog(494002) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • domestic cat(101082051) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • Thale Cress(821383) DNA mismatch repair protein Msh2
  • cow(533115) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • naked mole-rat(101706924) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • domestic guinea pig(100724489) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • sheep(101107944) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MSH2 Antibody, clone FE11, clone FE11, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-MSH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-MSH2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Rabbit anti-MSH2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
Anti-MSH2 antibody, Rabbit monoclonal, clone SP46, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
bovine, chicken, dog, human, mouse, pig, rat
Application
flow cytometry
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MSH2,
Species
human