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Merck

IGSF8

immunoglobulin superfamily, member 8

Synonyms:
CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL
Species:
UniProtKB ID:
Gene ID:
  • Human(93185) Summary: This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
  • Mouse(140559) immunoglobulin superfamily, member 8
  • Rat(304979) immunoglobulin superfamily, member 8
  • domestic guinea pig(100721506) immunoglobulin superfamily, member 8
  • naked mole-rat(101721418) immunoglobulin superfamily, member 8
  • sheep(101102283) immunoglobulin superfamily, member 8
  • Domestic Rabbit(100338663) immunoglobulin superfamily, member 8
  • Horse(100058209) immunoglobulin superfamily, member 8
  • cow(519266) immunoglobulin superfamily, member 8
  • dog(100855523) immunoglobulin superfamily, member 8
  • domestic cat(101097041) immunoglobulin superfamily, member 8

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IGSF8 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-IGSF8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-IGSF8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IGSF8,
Species
human
MISSION® esiRNA, targeting mouse Igsf8,
Species
mouse