GSTM5
glutathione S-transferase mu 5
Synonyms:
GSTM5-5, GTM5
Species:
UniProtKB ID:
Gene ID:
- Human(2949) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008]
- Mouse(14866) glutathione S-transferase, mu 5
- Rat(64352) glutathione S-transferase, mu 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GSTM5 antibody produced in mouse, clone 1G4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-GSTM5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GSTM5 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-GSTM5, (C-terminal) antibody produced in mouse, clone 1B3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Cell Lines
Product Number
Description
Species