CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
Synonyms:
CAMKK, CAMKKB
Species:
Human CAMKK2 (10645), Mouse Camkk2 (207565), Rat Camkk2 (83506), naked mole-rat Camkk2 (101723556), domestic guinea pig Camkk2 (100716041), sheep CAMKK2 (101103267), chicken CAMKK2 (396405), dog CAMKK2 (486263), cow CAMKK2 (509084), domestic cat CAMKK2 (101097674)
UniProtKB ID:
Gene ID:
- Human(10645) Summary: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
- Mouse(207565) calcium/calmodulin-dependent protein kinase kinase 2, beta
- Rat(83506) calcium/calmodulin-dependent protein kinase kinase 2, beta
- naked mole-rat(101723556) calcium/calmodulin-dependent protein kinase kinase 2, beta
- domestic guinea pig(100716041) calcium/calmodulin-dependent protein kinase kinase 2, beta
- sheep(101103267) calcium/calmodulin-dependent protein kinase kinase 2, beta
- chicken(396405) calcium/calmodulin-dependent protein kinase kinase 2, beta
- dog(486263) calcium/calmodulin-dependent protein kinase kinase 2, beta
- cow(509084) calcium/calmodulin-dependent protein kinase kinase 2, beta
- domestic cat(101097674) calcium/calmodulin-dependent protein kinase kinase 2, beta
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CAMKK2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CAMKK2, (N-terminal) antibody produced in mouse, clone 4C7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
ANTI-MOUSE CAMKK2 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
mouse
Application
western blot
Monoclonal Anti-CAMKK2 antibody produced in mouse, clone 1A11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CAMKK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species