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SYNTHIA™ Retrosynthesis Software

ACCELERATE YOUR RESEARCH AND RATE OF PATHWAY DISCOVERY FROM WEEKS TO MINUTES

Hand-coded by chemists and engineered by computer scientists, this synthetic planning tool draws from a profound chemical abstracts database of advanced organic synthesis rules and algorithms. Computer-aided synthesis allows you to rapidly generate synthetic routes to identified targets. ​

Based on years of development as Chematica, then further enhancement as SYNTHIA™, this software now enables chemists to easily navigate through viable pathways that can be executed at the bench.

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QUICKLY GO FROM IMAGINING WHAT’S POSSIBLE TO TESTING WHAT’S PROBABLE​

With this bench-validated retrosynthetic planning software, successfully design and plan routes for target molecules based on your requirements. ​

  • Select the type of retrosynthesis analysis to be performed and the target molecule from known and unknown compounds. ​
  • Customize search parameters: set a price threshold, protecting group preferences, scoring functions, stop conditions, and many more options. ​
  • Directly link to commercially available and known starting materials with price information and/or incorporate your custom inventory (patent pending). ​
  • Easily filter, sort, compare, and analyze custom pathways by viewing detailed molecule structures or graphs to explore the most cost-effective routes to chemical targets.

SYNTHIA™ RETROSYNTHESIS SOFTWARE WORKFLOW

Quickly go from imagining what’s possible to testing what’s probable with this novel chemical synthesis planning tool

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SELECT THE TYPE OF ANALYSIS

Choose between automatic computer-aided retrosynthesis or manual retrosynthesis

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CHOOSE A TARGET MOLECULE

Select from known and unknown compounds

 

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CUSTOMIZE SEARCH PARAMETERS

Define rules & filters, scoring functions, and stop conditions

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EXPLORE RESULTS

View detailed reaction information, post-filter routes, analyze pathways

SYNTHIA™ retrosynthesis software accounts for stereoselectivity and regioselectivity. This chemical synthesis planning tool presents the user with the most promising options by recognizing incompatibilities and avoiding nonviable synthetic steps that are possible but not practical.

Pioneer your pathway DISCOVERY WITH SYNTHIA™ RETROSYNTHESIS SOFTWARE​

Experience how SYNTHIA™ retrosynthesis software augments your expertise, saves time and reduces costs due to its profound Artificial Intelligence (AI) in chemistry. ​

​We offer customizable floating license packages and comprehensive service support. Contact us now for a quotation.​

PROVEN & PUBLISHED​

In the first successful laboratory validation of a retrosynthetic design software, SYNTHIA™ found robust and reliable pathways that reduced synthetic steps, increased yields, and decreased costs for both known and novel targets.

Efficient Syntheses of Diverse, Medicinally Relevant Targets Planned by Computer and Executed in the Laboratory
Navigating Around Patented Routes by Preserving Specific Motifs Along Computer-Planned Retrosynthetic Pathways
Algorithmic Discovery of Tactical Combinations for Advanced Organic Syntheses

Computer-generated “Synthetic Contingency” Plans at Times of Logistics and Supply Problems
Reinforcing the Supply Chain of COVID-19 Therapeutics with Expert-coded Retrosynthetic Software

Related Product Resources

Chematica: A Story of Computer Code That Started to Think like a Chemist
Brochure: Synthia™ Retrosynthesis Software
Webinar: Discover Recent Advances and Applications of SYNTHIA™

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