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Key Documents

SML2751

Sigma-Aldrich

UCSF7447

≥98% (HPLC)

Synonym(s):

2-Bromo-4-chloro-N-[3-(1H-1,2,4-triazol-5-yl)phenyl]-benzenemethanamine, ZINC555417447

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About This Item

Empirical Formula (Hill Notation):
C15H12BrClN4
CAS Number:
Molecular Weight:
363.64
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

UCSF7447 (ZINC555417447) brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor, which decelerates re-entrainment in mouse model of east-bound jetlag. Unexpectedly UCSF7447 advances the phase of the mouse circadian clock when administer at dusk.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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