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P5247

Sigma-Aldrich

Anti-Potassium Channel K2P9.1 (TASK3) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-Acid Sensitive Potassium Channel 3, Anti-KCNK9

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About This Item

MDL number:
MFCD06798510
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat, human

technique(s)

western blot: 1:200 using rat cerebellum lysate

UniProt accession no.

Q9NPC2

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... KCNK9(51305)
rat ... Kcnk9(84429)

Immunogen

synthetic peptide corresponding to amino acid residues 57-73 of rat K2P9.1. This sequence has 15/17 residues identical in human.

Physical form

Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.025% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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David Mu et al.
Cancer cell, 3(3), 297-302 (2003-04-05)
Representational difference analysis (RDA) of human breast cancer was used to discover a novel amplicon located at chromosomal region 8q24.3. We examined a series of breast cancer samples harboring amplification of this region and determined that KCNK9 is the sole
Inger Lauritzen et al.
The Journal of biological chemistry, 278(34), 32068-32076 (2003-06-05)
Rat mature cerebellar granule, unlike hippocampal neurons, die by apoptosis when cultured in a medium containing a physiological concentration of K+ but survive under high external K+ concentrations. Cell death in physiological K+ parallels the developmental expression of the TASK-1
Lin Pei et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(13), 7803-7807 (2003-06-05)
TASK3 gene (Kcnk9) is amplified and overexpressed in several types of human carcinomas. In this report, we demonstrate that a point mutation (G95E) within the consensus K+ filter of TASK3 not only abolished TASK3 potassium channel activity but also abrogated

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