TP53
tumor protein p53
Synonyms:
BCC7, LFS1, P53, TRP53
Species:
Human TP53 (7157), Rat Tp53 (24842), Zebrafish tp53 (30590), Horse TP53 (100062044), domestic cat TP53 (493847), dog TP53 (403869), chicken TP53 (396200), cow TP53 (281542), sheep TP53 (443421), domestic guinea pig Tp53 (100379269) ...More
UniProtKB ID:
Gene ID:
- Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
- Rat(24842) tumor protein p53
- Zebrafish(30590) tumor protein p53
- Horse(100062044) tumor protein p53
- domestic cat(493847) tumor protein p53
- dog(403869) tumor protein p53
- chicken(396200) tumor protein p53
- cow(281542) tumor protein p53
- sheep(443421) tumor protein p53
- domestic guinea pig(100379269) tumor protein p53
- Domestic Rabbit(100009292) tumor protein p53
- naked mole-rat(101701769) tumor protein p53
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-p53 antibody, Mouse monoclonal, clone BP53-12, ascites fluid,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Anti-TP53 (ab3) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, pig, rabbit, sheep
Application
ChIP
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-p53−Biotin antibody produced in mouse, ~1 mg/mL, clone DO-1, ascites fluid, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Acetyl (Lys 319) p53 Antibody, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-p53 (Acetyl-Lys379), C-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Cell Lines
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
p53 (1-342) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
p53 (1-363) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
esiRNA
Product Number
Description
Species