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Merck

PSMD7

proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

Synonyms:
MOV34, P40, Rpn8, S12
Species:
UniProtKB ID:
Gene ID:
  • Human(5713) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008]
  • Mouse(17463) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • Rat(307821) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • Zebrafish(327330) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)
  • dog(479671) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • domestic cat(101098912) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • chicken(415869) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • domestic guinea pig(100720798) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • naked mole-rat(101709806) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • cow(512456) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • sheep(101122881) proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PSMD7 antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-PSMD7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PSMD7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-PSMD7 antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PSMD7,
Species
human
MISSION® esiRNA, targeting mouse Psmd7,
Species
mouse