MBD1
methyl-CpG binding domain protein 1
Synonyms:
CXXC3, PCM1, RFT
Species:
Human MBD1 (4152), Mouse Mbd1 (17190), Rat Mbd1 (291439), Zebrafish mbd1 (334386), Thale Cress MBD1 (828371), domestic cat MBD1 (101089807), dog MBD1 (480218), Horse MBD1 (100053867), cow MBD1 (540558), domestic guinea pig Mbd1 (100724675) ...More
UniProtKB ID:
Gene ID:
- Human(4152) Summary: The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]
- Mouse(17190) methyl-CpG binding domain protein 1
- Rat(291439) methyl-CpG binding domain protein 1
- Zebrafish(334386) methyl-CpG binding domain protein 1
- Thale Cress(828371) methyl-CPG-binding domain 1
- domestic cat(101089807) methyl-CpG binding domain protein 1
- dog(480218) methyl-CpG binding domain protein 1
- Horse(100053867) methyl-CpG binding domain protein 1
- cow(540558) methyl-CpG binding domain protein 1
- domestic guinea pig(100724675) methyl-CpG binding domain protein 1
- naked mole-rat(101724111) methyl-CpG binding domain protein 1
- Domestic Rabbit(100340239) methyl-CpG binding domain protein 1
- sheep(101116619) methyl-CpG binding domain protein 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MBD1 antibody produced in mouse, clone 2C7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-MBD1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-MBD1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, rabbit, rat
Application
western blot
Anti-MBD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
esiRNA
Product Number
Description
Species