Skip to Content
Merck

GLI2

GLI family zinc finger 2

Synonyms:
HPE9, THP1, THP2
Species:
UniProtKB ID:
Gene ID:
  • Human(2736) Summary: This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
  • Mouse(14633) GLI-Kruppel family member GLI2
  • Rat(304729) GLI family zinc finger 2
  • domestic guinea pig(100715371) GLI family zinc finger 2
  • naked mole-rat(101697659) GLI family zinc finger 2
  • sheep(101114169) GLI family zinc finger 2
  • Domestic Rabbit(100359289) GLI family zinc finger 2
  • chicken(395956) GLI family zinc finger 2
  • dog(100682984) GLI family zinc finger 2
  • cow(510255) GLI family zinc finger 2
  • domestic cat(101101401) GLI family zinc finger 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GLI2 antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
Anti-GLI2, IgG fraction of antiserum,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-GLI2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-GLI2 antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
Anti-GLI2, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse GLI2,
Species
mouse