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Merck

ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

Synonyms:
EWWD, MRP8, WW
Species:
Human ABCC11 (85320), sheep ABCC11 (101115563), Domestic Rabbit ABCC11 (100359175), dog ABCC11 (478138), cow ABCC11 (100299784), cow ABCC11 (101909197), cow ABCC11 (522437), domestic cat ABCC11 (101089664)
UniProtKB ID:
Q96J66, Q8TDJ0, Q96JA6, Q9BX80
Gene ID:
  • Human(85320) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
  • sheep(101115563) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • Domestic Rabbit(100359175) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • dog(478138) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • cow(100299784) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • cow(101909197) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • cow(522437) ATP-binding cassette sub-family C member 11-like
  • domestic cat(101089664) ATP-binding cassette, sub-family C (CFTR/MRP), member 11

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2500647
Anti-MRP8/ABCC11 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human
Application
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
HPA031980
Anti-ABCC11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
SAB1403409
Monoclonal Anti-ABCC11 antibody produced in mouse, clone 4H6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
SAB1408146
Anti-ABCC11 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
SAB2105523
Anti-ABCC11 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
EHU065841
MISSION® esiRNA, targeting human ABCC11,
Species
human