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Amino acid salt catalyzed intramolecular Robinson annulation.

Chemical communications (Cambridge, England) (2009-09-03)
Pingfan Li, Hisashi Yamamoto
RESUMEN

The silica gel absorbed amino acid salt catalyzed asymmetric intramolecular Robinson annulation reaction has been developed; up to 97% ee was obtained with this readily recoverable organocatalyst.

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Sigma-Aldrich
1,4-Cyclohexanedimethanol, mixture of cis and trans, 99%