- Solid-phase synthesis in the twenty-first century.
Solid-phase synthesis in the twenty-first century.
Mini reviews in medicinal chemistry (2006-02-07)
A Ganesan
PMID16457628
RESUMEN
Solid-phase synthesis is a powerful tool for achieving high-throughput chemistry. This review discusses recent diverse examples from my group: the solid-phase synthesis of unsymmetrical guanidines, polymer-supported versions of cyclooctadiene and 9-BBN, a triflate-like linker, the synthesis of tetrahydro-beta-carbolines by the acyliminium Pictet-Spengler reaction, and a total synthesis of the antimycobacterial cyclic depsipeptide natural product kahalalide A.
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