SML1489
FICZ
≥95% (HPLC), lyophilized powder, AhR agonist
Sinónimos:
5,11-Dihydro-indolo[3,2-b]carbazole-6-carboxaldehyde, 6-Formylindolo[3,2-b]carbazole
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About This Item
Fórmula empírica (notación de Hill):
C19H12N2O
Número de CAS:
Peso molecular:
284.31
Código UNSPSC:
12352200
NACRES:
NA.77
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product name
FICZ, ≥95% (HPLC)
Nivel de calidad
Análisis
≥95% (HPLC)
formulario
lyophilized powder
color
yellow
solubilidad
DMSO: 0.5 mg/mL, clear (warmed)
temp. de almacenamiento
−20°C
Acciones bioquímicas o fisiológicas
FICZ (6-formylindolo(3,2b)carbazole) being a photooxidation product of tryptophan, might serve as a chemical messenger of light.
FICZ is a potent high affinity ligand of the aryl hydrocarbon receptor (AhR), which is a ligand-activated transcription factor that activates the expression of aromatic hydrocarbon metabolizing enzyme genes such as the CYP1A1 gene and has also been shown to have multiple additional roles in cell-cycle regulation, development and maturation of many tissues, control of inflammation, and immune response. FICZ is a photoproduct of tryptophan and is believed to be an endogenous AhR ligand. It is extremely potent, with a Kd value of 0.07 nM.
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 4 Oral
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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