SAB4503970

Anti-phospho-PLB (pSer^16+Thr17) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 6 kDa
• reactividad de especies: human, rat, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:1000; immunofluorescence: 1:100-1:500
• Nº de acceso NCBI: P26678
• Nº de acceso UniProt: P26678
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... PLN(5350)

Descripción

Descripción general

Phospholamban (PLN) gene codes for a small integral membrane protein. It is located on human chromosome 6q22.1. PLN is a 52-amino-acid phosphoprotein.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human PLB around the phosphorylation site of Ser16 and Thr17.

Immunogen Range: 1-50

Acciones bioquímicas o fisiológicas

Phospholamban (PLN) participates in calcium signalling and muscle contraction. This protein regulates the activity of the sarcoplasmic reticulum Ca²⁺-ATPase (SERCA) of cardiac myocytes. Mutations in the phospholamban (PLN) gene result in dilated cardiomyopathy (DCM) and severe heart failure.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable