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GW20079F

Sigma-Aldrich

Anti-Vitamin D-Binding Protein antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-VDBP

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

chicken

Nivel de calidad

200

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

reactividad de especies

human

técnicas

indirect ELISA: suitable
western blot: suitable

Nº de acceso NCBI

NP_000574.2

Nº de acceso UniProt

P02774

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... GC(2638)

Inmunógeno

Immunogen Sequence: GI # 32483410, sequence 1-474
Vitamin D-binding protein (native protein).

Aplicación

Anti-Vitamin D-Binding Protein antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Acciones bioquímicas o fisiológicas

Vitamin D-binding protein (also known as gc-globulin) is a protein encoded by the GC gene in humans. It transports vitamin D metabolites in the circulation. Both vitamin D metabolites and vitamin D binding proteins (VDBP) are associated with asthma (regulation in the lung during acute allergen-induced airway inflammation). Vitamin D-binding protein (VDBP) haplotypes also influence free vitamin D levels.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Aledie Navas-Nazario et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 112(6), 519-524 (2014-04-22)
Potential vitamin D-related influences on inflammatory diseases such as asthma are controversial, including the suggestion that vitamin D insufficiency is associated with increased asthma morbidity. Vitamin D-binding protein transports vitamin D metabolites in the circulation. Single nucleotide polymorphisms in the
A G Randolph et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 44(2), 231-237 (2014-01-23)
Between 75 000 and 125 000 U.S. infants are hospitalized for respiratory syncytial virus (RSV) bronchiolitis every year. Up to half will be diagnosed with asthma in later childhood. Vitamin D deficiency has been associated with susceptibility to asthma and respiratory infections.
K Bratke et al.
Clinical and experimental immunology, 177(1), 366-372 (2014-04-16)
Allergic asthma is a chronic disease of the airways associated with airway hyperresponsiveness, a variable degree of airflow obstruction, airway remodelling and a characteristic airway inflammation. Factors of the vitamin D axis, which include vitamin D metabolites and vitamin D

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