B352-05

Bovine Pulmonary Artery Smooth Muscle Cells: BPASMC (Cryovial)

• Código UNSPSC: 41106514
• NACRES: NA.81

Propiedades

• origen biológico: bovine pulmonary artery (tunica intima and media)
• envase: pkg of 500,000 cells
• fabricante / nombre comercial: Cell Applications, Inc
• modo de crecimiento: Adherent
• cariotipo: 2n = 60
• morfología: smooth muscle
• técnicas: cell culture | mammalian: suitable
• enfermedades relevantes: cardiovascular diseases
• Condiciones de envío: dry ice
• temp. de almacenamiento: −196°C

Descripción

Descripción general

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BPASMC have been used in studies relevant to pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells, the process shown to be mediated by hypoxia-induced expression of Bcl-xl (Suzuki, 2007). Additionally, they were used to elucidate the PKC-α dependent mechanisms of proMMP-2 activation and other signaling events in smooth muscle cells under pro-inflammatory conditions related to cell growth (Chakraborti, 2009; Roy, 2011, 2013; Dey, 2012; Chowdhury, 2013; Shaikh, 2013).

Characterization: positive for smooth muscle cell specific alpha-actin expression.

Origen línea celular

Artery

Aplicación

cell growth, signaling, receptor transactivation and suppression, vascular remodeling

Componentes

Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO

Nota de preparación

• 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 16 doublings

Rutina de subcultivo

Please refer to the BPASMC Culture Protocol.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable